Description

2-tert-Butyl-2H-1,2,3,4-Tetrazole-5-Carboxylic Acid is a specialized heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique tetrazole ring system, which is a bioisostere for carboxylic acids and other functional groups, enabling the fine-tuning of molecular properties in target compounds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting metabolic diseases, inflammation, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the tetrazole moiety can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, ligands for catalysis, and metal-organic frameworks (MOFs) due to its chelating and coordinating properties.
• Chemical Biology & Proteomics: Acts as a versatile click chemistry handle or a bioisosteric replacement in probe and linker molecules for studying biological systems.
• Energetic Materials Research: Investigated as a component in the design of new, high-nitrogen-content energetic compounds and propellants.

Basic Information

Product Name	2-tert-Butyl-2H-1,2,3,4-Tetrazole-5-Carboxylic Acid
CAS No.	1547646-28-5
Molecular Formula	C6H10N4O2
Molecular Weight	170.17 g/mol
Synonyms	2-(tert-Butyl)-2H-tetrazole-5-carboxylic acid; 5-Carboxy-2-tert-butyl-2H-tetrazole; 2-tert-Butyl-1,2,3,4-tetrazole-5-carboxylic acid; 2-tert-Butyltetrazole-5-carboxylic acid; 2H-Tetrazole-5-carboxylic acid, 2-(1,1-dimethylethyl)-; 2-tert-Butyl-2H-tetrazole-5-carboxylic acid; tert-Butyl tetrazole-5-carboxylate (tautomer); 1547646-28-5
EINECS	Contact for details

Quality Control

Our production of 2-tert-Butyl-2H-1,2,3,4-Tetrazole-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All materials are characterized by modern analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.