Description

5-(Aminomethyl)-2-Chlorophenylboronic Acid Pinacol Ester is a versatile and highly functionalized boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the synergistic combination of a protected boronic acid group for Suzuki-Miyaura cross-coupling and a primary amine moiety for further derivatization, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions, particularly for creating biaryl structures common in drug molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require complex, halogenated aromatic scaffolds.
• Material Science Building Block: Employed in the creation of organic electronic materials, such as those for OLEDs or conductive polymers, where precise molecular structure is critical.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel bidentate ligands or metal-organic frameworks (MOFs) due to its dual functional groups.
• Bioconjugation and Probe Synthesis: The amine group allows for attachment to biomolecules or fluorescent tags, making it useful for creating diagnostic probes or targeted delivery systems.
• Custom Chemical Synthesis: Essential for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	5-(Aminomethyl)-2-Chlorophenylboronic Acid Pinacol Ester
CAS No.	1544673-71-3
Molecular Formula	C13H19BClNO2
Molecular Weight	267.56 g/mol
Synonyms	2-Chloro-5-(aminomethyl)phenylboronic acid pinacol ester; (5-(Aminomethyl)-2-chlorophenyl)boronic acid pinacol ester; 2-Chloro-5-(aminomethyl)benzeneboronic acid pinacol ester; 1544673-71-3; 5-(Aminomethyl)-2-chloro-benzeneboronic acid pinacol ester; Pinacol [5-(aminomethyl)-2-chlorophenyl]boronate
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2-Chlorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.