Description

(2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-purity boronic ester derivative, a critical advanced intermediate in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive pinacol boronate ester group with a benzylic alcohol, enabling precise carbon-carbon bond formation and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the boronate group for efficient coupling with heterocyclic systems.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other advanced organic electronic components through cross-coupling polymerization.
• Ligand & Catalyst Preparation: The benzylic alcohol moiety can be modified to create novel chiral or bidentate ligands for asymmetric catalysis and transition metal complexes.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological processes and diagnostic applications.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Item	Details
Product Name	(2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No.	1544673-46-2
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	5-(Hydroxymethyl)-2-methylphenylboronic acid pinacol ester; (5-(Hydroxymethyl)-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; [5-(Hydroxymethyl)-2-methylphenyl]boronic acid pinacol ester; (5-Hydroxymethyl-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-5-(pinacolboryl)benzyl alcohol; 1544673-46-2
EINECS	Contact for details

Quality Control

Our (2-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (¹H and ¹³C), and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for GMP and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent hydrolysis of the boronate ester. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.