Description

4'-Bromo-3',5'-Difluoroacetophenone is a high-purity, multi-functional halogenated aromatic ketone building block. This compound is valued for its unique molecular architecture, which enables precise chemical modifications in advanced synthetic pathways. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromo and difluoro substituents contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and liquid crystals, leveraging its aromatic core and functional handles.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and bio-imaging applications.

Basic Information

Product Name	4'-Bromo-3',5'-Difluoroacetophenone
CAS No.	1528607-78-4
Molecular Formula	C8H5BrF2O
Molecular Weight	235.03 g/mol
Synonyms	1-(4-Bromo-3,5-difluorophenyl)ethanone; 3',5'-Difluoro-4'-bromoacetophenone; 4-Bromo-3,5-difluoroacetophenone; 1-Acetyl-4-bromo-3,5-difluorobenzene; 4-Bromo-3,5-difluoroacetophenone; 4'-Bromo-3',5'-difluoroacetophenone; 1528607-78-4
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3',5'-Difluoroacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.