Description

[4-(Adamantan-1-Yl)Phenyl]Boronic Acid is a high-purity organoboron compound featuring a rigid adamantyl group, making it a valuable building block for advanced organic synthesis. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex biaryl structures with high efficiency and selectivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, leveraging the lipophilic and metabolically stable adamantane moiety.
• Agrochemical Synthesis: Used in creating novel fungicides and herbicides where the adamantyl-phenyl scaffold contributes to improved environmental stability and biological activity.
• Materials Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and metal-organic frameworks (MOFs) with tailored properties.
• Catalyst Ligand Development: The boronic acid group can be utilized to create sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	[4-(Adamantan-1-Yl)Phenyl]Boronic Acid
CAS No.	1527479-23-7
Molecular Formula	C16H21BO2
Molecular Weight	256.15 g/mol
Synonyms	4-(1-Adamantyl)phenylboronic Acid; (4-Adamantan-1-ylphenyl)boronic Acid; B-[4-(1-Adamantyl)phenyl]boronic Acid; 4-(Tricyclo[3.3.1.13,7]decan-1-yl)benzeneboronic Acid; p-Adamantylphenylboronic Acid; 1-(4-Boronophenyl)adamantane; Adamantylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our [4-(Adamantan-1-Yl)Phenyl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.