Description

Ethyl 1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Cyclopropane-1-Carboxylate is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing cyclopropane and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage the unique properties of the cyclopropane ring.
• Material Science Research: Acts as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester functionality is specifically designed for palladium-catalyzed cross-coupling to form carbon-carbon bonds with high fidelity.
• Medicinal Chemistry & Library Synthesis: Enables the rapid parallel synthesis of diverse compound libraries for high-throughput screening in drug discovery programs.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Item	Detail
Product Name	Ethyl 1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Cyclopropane-1-Carboxylate
CAS No.	1521255-61-7
Molecular Formula	C20H29BO4
Molecular Weight	344.26 g/mol
Synonyms	Ethyl 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarboxylate; 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylic acid ethyl ester; 3-(Ethoxycarbonylcyclopropyl)phenylboronic acid pinacol ester; (3-(Ethoxycarbonyl)cyclopropyl)phenylboronic acid pinacol ester; B-[3-(1-Ethoxycarbonylcyclopropyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Ethyl 1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Cyclopropane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.