Description

Methyl 2-Cyclobutyl-2-Hydroxyacetate is a specialized chiral building block and ester derivative of significant interest in advanced organic synthesis. Its core value lies in the presence of both a cyclobutyl group and a reactive hydroxyacetate moiety, making it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the cyclobutyl ring confers specific biological activity.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and ring-strain chemistry.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Methyl 2-Cyclobutyl-2-Hydroxyacetate
CAS No.	1517761-58-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	Methyl α-hydroxycyclobutanacetate; 2-Hydroxy-2-cyclobutylacetic acid methyl ester; Methyl (2-hydroxy-2-cyclobutyl)acetate; Cyclobutaneglycolic acid methyl ester; (2-Hydroxy-2-cyclobutyl)acetic acid methyl ester; 2-Cyclobutyl-2-hydroxyacetic acid methyl ester; Methyl 2-hydroxy-2-cyclobutylacetate; Acetic acid, 2-cyclobutyl-2-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Cyclobutyl-2-Hydroxyacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.