Description

1-Bromo-4-Fluoro-2-(4-Nitrophenoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, offering precise bromo, fluoro, and nitrophenoxy functional handles for regioselective coupling and derivatization. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the creation of specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure for bioactivity.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic chemistry.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags, photoaffinity labels, and other molecular probes for biochemical research.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis, including Suzuki-Miyaura and Buchwald-Hartwig coupling reactions.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-(4-Nitrophenoxy)Benzene
CAS No.	1516580-07-6
Molecular Formula	C12H7BrFNO3
Molecular Weight	312.10 g/mol
Synonyms	4-Bromo-1-fluoro-2-(4-nitrophenoxy)benzene; 2-(4-Nitrophenoxy)-4-bromo-1-fluorobenzene; 1-Bromo-4-fluoro-2-(4-nitrophenoxy)benzene; Benzene, 1-bromo-4-fluoro-2-(4-nitrophenoxy)-; 4-Nitrophenyl 4-bromo-2-fluorophenyl ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2-(4-Nitrophenoxy)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.