Description

4-Methyl-3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Boronic Acid is a high-value, multifunctional heterocyclic boronic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a crucial boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science & OLED Development: Serves as a building block for creating organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
• Chemical Biology & Probe Synthesis: Utilized in the creation of molecular probes and sensors for studying biological processes and enzyme activity.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	4-Methyl-3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Boronic Acid
CAS No.	1515875-37-2
Molecular Formula	C9H10BNO4
Molecular Weight	206.99 g/mol
Synonyms	7-Borono-4-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one; 4-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-boronic acid; 4-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-boronic acid pinacol ester (common precursor); Benzo[1,4]oxazin-7-boronic acid, 3,4-dihydro-4-methyl-3-oxo-; 1515875-37-2; Benzoxazine boronic acid derivative
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for advanced intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.