Description

7-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine is a high-value, heterocyclic boronic ester derivative, serving as a critical advanced pharmaceutical intermediate and building block in modern organic synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex carbon-carbon bonds. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for target identification and validation in biological systems.
• Cross-Coupling Reactions: A versatile reagent for Suzuki-Miyaura coupling to introduce the pyridooxazine moiety into complex molecular architectures.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine
CAS No.	1515866-60-0
Molecular Formula	C15H21BN2O3
Molecular Weight	288.15 g/mol
Synonyms	2,3-Dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-ylboronic acid pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine; 7-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydropyrido[2,3-b][1,4]oxazine; Pyrido[2,3-b][1,4]oxazine-7-boronic acid pinacol ester; CAS 1515866-60-0; 1515866-60-0
EINECS	Contact for details

Quality Control

Our 7-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.