Description

Benzamide, n-(2-Methylpropyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a specialized boronic ester derivative of a substituted benzamide, serving as a critical building block in modern synthetic chemistry. Its value lies in the combination of the amide functional group with the versatile boronate ester, which is highly reactive in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the boronate group for efficient carbon-carbon bond formation.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a probe or linker in bioconjugation chemistry and the development of enzyme inhibitors or activity-based probes.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Intermediate for the manufacture of complex, high-value specialty chemicals used in various industrial applications.

Basic Information

Product Name	Benzamide, n-(2-Methylpropyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1509932-23-3
Molecular Formula	C17H26BNO3
Molecular Weight	303.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-isobutylbenzamide; N-Isobutyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 4-Pinacolatoboron-N-isobutylbenzamide; 4-Boronobenzamide, N-isobutyl-, pinacol ester; Benzamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-methylpropyl)-; 1509932-23-3; Isobutyl-4-boronic acid pinacol ester benzamide
EINECS	Contact for details

Quality Control

Our production of Benzamide, n-(2-Methylpropyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to confirm identity and quantify purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronate ester. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.