Description

4-Chloro-5-Iodo-2-Methoxyaniline is a halogenated aniline derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), functional dyes, and specialized ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with specific halogenated motifs.
• Material Science: Used in the creation of organic semiconductors, liquid crystals, and photoresist materials due to its electron-rich aniline core and halogen substituents.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized azo dyes and pigments where the chloro and iodo groups influence color fastness and spectral properties.
• Chemical Research: Valuable reagent in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a scaffold for library synthesis in medicinal chemistry.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chelating ligands used in homogeneous catalysis.

Basic Information

Product Name	4-Chloro-5-Iodo-2-Methoxyaniline
CAS No.	1508278-49-6
Molecular Formula	C7H7ClINO
Molecular Weight	283.49 g/mol
Synonyms	2-Methoxy-4-chloro-5-iodoaniline; 4-Chloro-5-iodo-2-methoxybenzenamine; 5-Iodo-4-chloro-2-methoxyaniline; 2-Amino-5-chloro-4-iodoanisole; 4-Chloro-5-iodo-o-anisidine; Benzenamine, 4-chloro-5-iodo-2-methoxy-; 1508278-49-6
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Iodo-2-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.