Description

[3-(2-Fluorophenyl)Oxetan-3-Yl]Methanamine is a high-value, fluorinated oxetane building block used in advanced organic synthesis. This compound matters for its unique structural motif, which combines a constrained oxetane ring with a fluorinated aromatic system, offering opportunities to modulate the physicochemical properties of target molecules. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, where it serves as a key intermediate in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies to optimize potency, metabolic stability, and bioavailability of lead compounds.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for investigating biological pathways and target validation.
• Material Science: Potential monomer or additive for creating specialized polymers with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates at various scales.

Basic Information

Product Name	[3-(2-Fluorophenyl)Oxetan-3-Yl]Methanamine
CAS No.	1507868-26-9
Molecular Formula	C10H12FNO
Molecular Weight	181.21 g/mol
Synonyms	1-((3-(2-Fluorophenyl)oxetan-3-yl)methyl)amine; 3-(Aminomethyl)-3-(2-fluorophenyl)oxetane; (3-(2-Fluorophenyl)oxetan-3-yl)methanamine; 2-Fluoro-α-(aminomethyl)benzenemethanol cyclic ether; Oxetane-3-methanamine, 3-(2-fluorophenyl)-; 3-(2-Fluorobenzene)oxetane-3-methanamine
EINECS	Contact for details

Quality Control

Our [3-(2-Fluorophenyl)Oxetan-3-Yl]Methanamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. While typically supplied at research-grade purity (>95%), specifications can be tailored to meet specific project requirements, including higher purity grades for advanced screening.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.