Description

L-Erythro-Hexuronic Acid, 3,5-Dideoxy-, 1,1-Dimethylethyl Ester is a high-purity, protected sugar acid derivative, specifically a tert-butyl ester, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex bioactive molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on nucleoside analogs, carbohydrate-based therapeutics, and other fine chemical intermediates where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral or anticancer drug candidates.
• Carbohydrate Chemistry Research: Used as a protected intermediate for the study and synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Process Chemistry & Scale-up: Serves as a defined starting material for optimizing synthetic routes in kilo-lab and pilot plant production of active pharmaceutical ingredients (APIs).
• Biochemical Probe Development: Utilized in creating labeled or modified sugar acids for metabolic pathway studies and enzyme inhibition assays.
• Fine Chemical Synthesis: Building block for producing specialty chemicals requiring specific hexuronic acid derivatives with high enantiomeric purity.

Basic Information

Item	Details
Product Name	L-Erythro-Hexuronic Acid, 3,5-Dideoxy-, 1,1-Dimethylethyl Ester
CAS No.	1501982-84-8
Molecular Formula	C10H16O5
Molecular Weight	216.23 g/mol
Synonyms	1,1-Dimethylethyl 3,5-dideoxy-L-erythro-hex-2-enuronate; tert-Butyl 3,5-dideoxy-L-erythro-hex-2-enuronate; 3,5-Dideoxy-L-erythro-hex-2-enuronic acid tert-butyl ester; L-erythro-Hex-2-enuronic acid, 3,5-dideoxy-, 1,1-dimethylethyl ester; Protected L-Hexuronic Acid Ester; Chiral Sugar Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our L-Erythro-Hexuronic Acid, 3,5-Dideoxy-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.