Description

4-Fluoro-3,3-Dimethyl-2,3-Dihydro-1H-Inden-1-One is a high-value fluorinated indanone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a fluorine atom and a ketone group on a fused ring system, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its scaffold can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers and organic electronic materials.
• Ligand and Catalyst Synthesis: Employed in the creation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing novel aromatic compounds with specific olfactory profiles.

Basic Information

Product Name	4-Fluoro-3,3-Dimethyl-2,3-Dihydro-1H-Inden-1-One
CAS No.	1501959-50-7
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	4-Fluoro-3,3-dimethylindan-1-one; 1H-Inden-1-one, 4-fluoro-3,3-dihydro-3,3-dimethyl-; 3,3-Dimethyl-4-fluoro-2,3-dihydro-1H-inden-1-one; 4-Fluoro-3,3-dimethyl-2,3-dihydroinden-1-one; 4-Fluoro-3,3-dimethylindanone; FC-1137 (Research Code); AKOS BRN-0972
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3,3-Dimethyl-2,3-Dihydro-1H-Inden-1-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee it meets your specific research or production-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.