Description

1-(3-Bromophenyl)-3,3-Dimethoxycyclobutane-1-Carbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutane core functionalized with bromophenyl and nitrile groups. This compound is valued for its role as a critical building block in the synthesis of complex, bioactive molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions and pharmaceutical companies developing novel therapeutic agents, where its specific stereochemistry and functional groups are essential for creating target compounds with desired biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents and pesticides.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex organic molecules, leveraging its reactive nitrile and bromine functional groups for further derivatization.

Basic Information

Product Name	1-(3-Bromophenyl)-3,3-Dimethoxycyclobutane-1-Carbonitrile
CAS No.	1494527-01-3
Molecular Formula	C13H14BrNO2
Molecular Weight	296.16 g/mol
Synonyms	3-Bromophenyl-3,3-dimethoxycyclobutane-1-carbonitrile; 1-(3-Bromophenyl)-3,3-dimethoxycyclobutanecarbonitrile; 3,3-Dimethoxy-1-(3-bromophenyl)cyclobutane-1-carbonitrile; Cyclobutanecarbonitrile, 1-(3-bromophenyl)-3,3-dimethoxy-; 1494527-01-3; 1-(3-Bromophenyl)-3,3-dimethoxycyclobutyl cyanide
EINECS	Contact for details

Quality Control

Our production of 1-(3-Bromophenyl)-3,3-Dimethoxycyclobutane-1-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. Each lot is thoroughly characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.