Description

4,4,5,5-Tetramethyl-2-[5-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Thiophen-2-Yl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, offering both a protected boronic acid group and a thiophene moiety, making it an indispensable reagent for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling reactions and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require complex heterocyclic structures.
• Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Material Science Research: Enables the creation of novel organic frameworks and functional materials with tailored electronic properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for imaging and diagnostic applications.
• Academic & Process R&D: A valuable reagent for methodology development and scaling up novel synthetic routes in research laboratories.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[5-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Thiophen-2-Yl]-1,3,2-Dioxaborolane
CAS No.	1492038-20-6
Molecular Formula	C19H31BO4S
Molecular Weight	366.33 g/mol
Synonyms	2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5,5'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolane-2,2-diyl)bis(thiophene-2-carboxaldehyde) derivative; Thiophene-2,5-diboronic acid bis(pinacol) ester; 2,5-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; Thiophene-2,5-diylbis(boronic acid pinacol ester); 2,5-Diboronic acid thiophene pinacol ester; 2,5-Thiophenediboronic acid bis(1,1,2,2-tetramethylethylene glycol) ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[5-(4,4,5,5-Tetramethyl-1,3-Dioxolan-2-Yl)Thiophen-2-Yl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity suitable for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing under an inert gas blanket in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.