Description

2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazol-1-Yl)Ethanol is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl structures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those containing benzimidazole scaffolds with tailored side chains.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl/heteroaryl halides and the boronic ester moiety under palladium catalysis.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Biology & Probe Synthesis: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazol-1-Yl)Ethanol
CAS No.	1491137-94-0
Molecular Formula	C15H21BN2O3
Molecular Weight	288.15 g/mol
Synonyms	2-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazol-1-yl]ethanol; 1H-Benzimidazol-1-ethanol, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole-1-ethanol; 2-(5-(Pinacolatoboryl)-1H-benzo[d]imidazol-1-yl)ethanol; 5-Pinacolatoboryl-1H-benzimidazole-1-ethanol; 1491137-94-0; Benzimidazole boronic ester pinacol derivative
EINECS	Contact for details

Quality Control

Our 2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Benzo[D]Imidazol-1-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This compound is hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.