Description

2-Morpholino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific aryl-boron motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular engineering is crucial.
• Chemical Biology & Probe Development: Serves as a versatile precursor for synthesizing fluorescent tags, bioconjugation reagents, and molecular probes.
• Academic & Industrial R&D: A staple reagent in laboratory-scale and process chemistry for method development and scaling novel synthetic routes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and specialty fine chemicals.

Basic Information

Item	Details
Product Name	2-Morpholino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
CAS No.	1488411-05-7
Molecular Formula	C17H23BN2O3
Molecular Weight	314.19 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-morpholinobenzonitrile; 2-Morpholino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2-Morpholin-4-yl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 4-(2-Cyano-5-morpholinophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 2-Morpholino-4-cyanophenylboronate
EINECS	Contact for details

Quality Control

Our 2-Morpholino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.