Description

2-(3-Cyclopentyl-1-Propyn-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a pinacol boronic ester derivative, with CAS number 1487355-69-0. This compound is essential for advanced organic synthesis, enabling the efficient construction of complex molecular architectures through cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in pharmaceutical lead optimization.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific, complex chemical structures.
• Materials Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Facilitates the synthesis of probe molecules and labeled compounds for biological target identification and validation.
• Process Chemistry & Scale-Up: Provides a reliable and consistent reagent for transitioning from laboratory-scale discovery to pilot and commercial-scale manufacturing.

Basic Information

Product Name	2-(3-Cyclopentyl-1-Propyn-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1487355-69-0
Molecular Formula	C₁₄H₂₃BO₂
Molecular Weight	234.14 g/mol
Synonyms	2-(3-Cyclopentylprop-1-yn-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Cyclopentyl-1-propyn-1-ylboronic acid pinacol ester; (3-Cyclopentylprop-1-yn-1-yl)boronic acid pinacol ester; Cyclopentylpropynyl pinacol boronate; Pinacol (3-cyclopentylprop-1-yn-1-yl)boronate; 1487355-69-0; Cyclopentyl Alkynyl Pinacol Boronate Ester
EINECS	Contact for details

Quality Control

Our 2-(3-Cyclopentyl-1-Propyn-1-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR and HPLC analysis, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.