Description

1-{[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}-1H-Imidazole is a sophisticated boronic ester derivative, a key building block in modern synthetic chemistry. This compound matters for its role as a versatile intermediate in cross-coupling reactions, enabling the precise construction of complex molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its boronate functionality for selective molecular assembly.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as polymers for OLEDs and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and probes for studying biological pathways and protein interactions.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligand systems used in homogeneous catalysis.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	1-{[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}-1H-Imidazole
CAS No.	1486485-39-5
Molecular Formula	C16H21BN2O2
Molecular Weight	284.16 g/mol
Synonyms	1-[(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]-1H-imidazole; 1-((3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-1H-imidazole; (3-((1H-Imidazol-1-yl)methyl)phenyl)boronic acid pinacol ester; 3-((1H-Imidazol-1-yl)methyl)benzeneboronic acid pinacol ester; 1-{[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]}-1H-imidazole; Pinacol [3-((1H-imidazol-1-yl)methyl)phenyl]boronate; 1486485-39-5
EINECS	Contact for details

Quality Control

Our 1-{[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.