Description

{3-Methyl-[1,2,4]Triazolo[4,3-A]Pyridin-7-Yl}Boronic Acid is a high-purity, heterocyclic boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeted therapies and small molecule inhibitors.
• Agrochemical Research: Used in constructing complex molecular scaffolds for new herbicides, fungicides, and insecticides.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, via cross-coupling reactions.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Process Chemistry: Used in scaling up synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	{3-Methyl-[1,2,4]Triazolo[4,3-A]Pyridin-7-Yl}Boronic Acid
CAS No.	1471260-44-2
Molecular Formula	C7H8BN3O2
Molecular Weight	176.97 g/mol
Synonyms	(3-Methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)boronic acid; 3-Methyl-[1,2,4]triazolo[4,3-a]pyridine-7-boronic acid; 7-Borono-3-methyl-[1,2,4]triazolo[4,3-a]pyridine; B-(3-Methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)boronic acid; 3-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine (Pinacol ester precursor)
EINECS	Contact for details

Quality Control

Our {3-Methyl-[1,2,4]Triazolo[4,3-A]Pyridin-7-Yl}Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.