Description

1-Propanesulfonamide, n-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-purity, advanced pharmaceutical intermediate and chemical building block. This compound is valued for its unique molecular structure, which combines a sulfonamide moiety with a pinacol boronate ester, making it a versatile synthon for Suzuki-Miyaura cross-coupling reactions. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the boronate group for structural diversification.
• Material Science: Serves as a precursor for creating functional polymers and organic electronic materials with tailored properties.
• Chemical Synthesis: A crucial reagent in palladium-catalyzed cross-coupling reactions (Suzuki-Miyaura) to form biaryl and heterobiaryl structures.
• Life Science Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Diagnostic Reagent Development: Potential use in synthesizing probes and sensors for biochemical assays.

Basic Information

Item	Details
Product Name	1-Propanesulfonamide, n-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	1469930-91-3
Molecular Formula	C15H24BNO4S
Molecular Weight	325.23 g/mol
Synonyms	N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1-propanesulfonamide; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(propylsulfonyl)aniline; 1-Propanesulfonamide, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; B-[3-[(Propylsulfonyl)amino]phenyl]boronic acid pinacol ester; 3-[(Propylsulfonyl)amino]phenylboronic acid pinacol ester; Boronic acid, B-[3-[(propylsulfonyl)amino]phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-Propanesulfonamide, n-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.