Description

(1-Fluorocyclopropyl)Methanamine Hydrochloride is a high-purity fluorinated amine building block essential for modern pharmaceutical and agrochemical research. Its value lies in the unique reactivity and metabolic stability imparted by the fluorocyclopropyl moiety, enabling the development of novel bioactive compounds. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorinated cyclopropane ring enhances biological activity and environmental persistence.
• Fluorine Chemistry Building Block: Serves as a versatile precursor for introducing the fluorocyclopropylamine group into more complex molecules via amide coupling, reductive amination, or nucleophilic substitution reactions.
• Ligand and Catalyst Development: Employed in the creation of chiral amines and ligands for asymmetric catalysis in fine chemical synthesis.
• Peptidomimetics and Bio-conjugates: Incorporated into peptide backbones or used as a linker to modify peptides and proteins, altering their stability and binding properties.
• Material Science Research: Potential monomer or functionalization agent for specialty polymers and advanced materials requiring specific surface properties.

Basic Information

Item	Details
Product Name	(1-Fluorocyclopropyl)Methanamine Hydrochloride
CAS No.	1462885-86-4
Molecular Formula	C4H9ClFN
Molecular Weight	125.57 g/mol
Synonyms	1-(Aminomethyl)-1-fluorocyclopropane Hydrochloride; (1-Fluorocyclopropyl)methylamine Hydrochloride; 1-Fluorocyclopropanemethylamine HCl; (Aminomethyl)fluorocyclopropane Hydrochloride; Fluorocyclopropylmethylamine Hydrochloride; 1-Fluoro-1-(aminomethyl)cyclopropane Hydrochloride
EINECS	Contact for details

Quality Control

Our (1-Fluorocyclopropyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.