Description

(1-Fluorocyclopentyl)Methanamine Hydrochloride is a high-purity fluorinated amine hydrochloride salt, a key building block in modern synthetic chemistry. Its value lies in its unique structure, which incorporates both a cyclopentyl ring and a fluorine atom, making it a versatile intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Organic Synthesis Reagent: Acts as a versatile precursor for constructing complex molecular architectures in medicinal chemistry and material science research.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The fluorinated cyclopentylamine moiety is valuable for designing peptide mimics and bioisosteric replacements in drug discovery.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(1-Fluorocyclopentyl)Methanamine Hydrochloride
CAS No.	1462885-83-1
Molecular Formula	C6H13ClFN
Molecular Weight	153.63 g/mol
Synonyms	1-(Aminomethyl)-1-fluorocyclopentane hydrochloride; (1-Fluorocyclopentyl)methylamine hydrochloride; 1-Fluorocyclopentanemethanamine hydrochloride; (Aminomethyl)(1-fluorocyclopentane) hydrochloride; 1-Fluoro-1-(aminomethyl)cyclopentane hydrochloride; α-(Aminomethyl)-α-fluorocyclopentane hydrochloride
EINECS	Contact for details

Quality Control

Our (1-Fluorocyclopentyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.