Description

(2-Chloro-5-Iodophenyl)(4-Methoxyphenyl)Methanone is a high-purity, halogenated diaryl ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents on one aromatic ring and a methoxy group on the other, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a scaffold for further functionalization in organic chemistry R&D.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and in the study of structure-activity relationships (SAR).

Basic Information

Product Name	(2-Chloro-5-Iodophenyl)(4-Methoxyphenyl)Methanone
CAS No.	1459754-39-2
Molecular Formula	C14H10ClIO2
Molecular Weight	372.59 g/mol
Synonyms	2-Chloro-5-iodobenzophenone, 4'-Methoxy-2-chloro-5-iodobenzophenone; 4-Methoxyphenyl(2-chloro-5-iodophenyl)methanone; (2-Chloro-5-iodophenyl)(4-methoxyphenyl)methanone; 1-(2-Chloro-5-iodophenyl)-1-(4-methoxyphenyl)methanone; Benzophenone, 2-chloro-5-iodo-4'-methoxy-; 4'-Methoxy-2-chloro-5-iodobenzophenone
EINECS	Contact for details

Quality Control

Our production of (2-Chloro-5-Iodophenyl)(4-Methoxyphenyl)Methanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.