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Potassium [1,1'-Biphenyl]-2-Yltrifluoroborate CAS NO 1456913-20-4
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CAS No.:1456913-20-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Potassium [1,1'-Biphenyl]-2-Yltrifluoroborate is an organotrifluoroborate salt, a highly valuable class of reagents in modern synthetic chemistry. This compound matters as a stable, air- and moisture-tolerant alternative to sensitive boronic acids, enabling critical carbon-carbon bond-forming reactions with superior handling characteristics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex biphenyl architectures and other aryl-containing molecules.
Application
- Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed coupling with aryl halides or triflates to synthesize biaryl compounds, a core structure in many active pharmaceutical ingredients (APIs).
- Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of drug candidates, particularly those requiring functionalized biphenyl moieties.
- Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides that incorporate biphenyl units for enhanced efficacy.
- Ligand and Catalyst Preparation: Serves as a building block for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in catalysis.
- Material Science Research: Utilized in the development of organic electronic materials, such as those for OLEDs and semiconductors, where conjugated biphenyl systems are fundamental.
- Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for imaging and diagnostic applications.
Basic Information
| Product Name | Potassium [1,1'-Biphenyl]-2-Yltrifluoroborate |
| CAS No. | 1456913-20-4 |
| Molecular Formula | C12H9BF3K |
| Molecular Weight | 260.11 g/mol |
| Synonyms | Potassium 2-Biphenylyltrifluoroborate; 2-Biphenyltrifluoroborate Potassium Salt; Potassium (Biphenyl-2-yl)trifluoroborate; [1,1'-Biphenyl]-2-yltrifluoroboronic Acid Potassium Salt; 2-Phenylphenyltrifluoroborate Potassium Salt; 2-Biphenylyl Potassium Trifluoroborate; Potassium (2-Phenylphenyl)trifluoroborate; Biphenyl-2-yl-BF3K |
| EINECS | Contact for details |
Quality Control
Our Potassium [1,1'-Biphenyl]-2-Yltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high chemical purity and consistent performance in cross-coupling reactions. Certificates of Analysis (COA) with detailed specifications are available for every lot upon request, supporting your quality assurance and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| 11B NMR Purity | ≥ 97% |
| Water Content (KF) | ≤ 2.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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