Description

4-Amino-3-Chloro-5-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique molecular architecture, featuring three distinct reactive sites—amino, chloro, and nitro groups—which enable versatile synthetic transformations. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro substituents for bioactivity.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized azo dyes and organic pigments due to its amino and nitro functional groups.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The chloro substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination.
• Chemical Research & Development: A versatile reagent for exploring new organic synthesis pathways and creating custom chemical libraries.

Basic Information

Product Name	4-Amino-3-Chloro-5-Nitrobenzonitrile
CAS No.	1456531-72-8
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	3-Chloro-4-amino-5-nitrobenzonitrile; 5-Nitro-3-chloro-4-aminobenzonitrile; Benzonitrile, 4-amino-3-chloro-5-nitro-; 4-Amino-3-chloro-5-nitro-benzonitrile; 2-Chloro-6-cyano-3-nitroaniline; 3-Chloro-4-cyano-2-nitroaniline; 4-Amino-3-chloro-5-nitrobenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.