Description

1,1,1-Trifluoro-3-{[(4-Methoxyphenyl)Methyl]Amino}Propan-2-Ol is a high-value fluorinated amino alcohol building block, characterized by its trifluoromethyl group and methoxyphenyl moiety. This compound is critical for pharmaceutical and agrochemical research, where its unique structure enables the introduction of fluorine to enhance metabolic stability, bioavailability, and binding affinity. It is primarily sought by R&D chemists and process development scientists in the fine chemical and advanced material sectors for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in CNS, oncology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom improves lipophilicity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals with unique surface properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biological molecules for mechanistic and metabolic studies.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis projects and scale-up services for clients requiring fluorinated compounds.

Basic Information

Product Name	1,1,1-Trifluoro-3-{[(4-Methoxyphenyl)Methyl]Amino}Propan-2-Ol
CAS No.	1456421-08-1
Molecular Formula	C11H14F3NO2
Molecular Weight	249.23 g/mol
Synonyms	1,1,1-Trifluoro-3-[(4-methoxybenzyl)amino]propan-2-ol; 3-[(4-Methoxybenzyl)amino]-1,1,1-trifluoropropan-2-ol; 2-Propanol, 1,1,1-trifluoro-3-[[(4-methoxyphenyl)methyl]amino]-; 1,1,1-Trifluoro-3-(4-methoxybenzylamino)propan-2-ol; Trifluoromethyl Amino Alcohol Derivative; 4-Methoxybenzylamino-trifluoropropanol; F3C-CH(OH)CH2NHCH2C6H4OCH3 (p)
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-3-{[(4-Methoxyphenyl)Methyl]Amino}Propan-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its chemical nature, keep away from strong alkalis and incompatible materials. For long-term storage, consider under an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.