Description

n-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenemethanamine is a high-purity, advanced pharmaceutical intermediate featuring a versatile boronic ester pinacol group. This compound is critical for facilitating efficient cross-coupling reactions, particularly in the synthesis of complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for creating biaryl and heterobiaryl structures in active pharmaceutical ingredient (API) development.
• Pharmaceutical Intermediate: Used in the research and synthesis of potential drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and organometallic chemistry.
• Material Science Research: Used in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and probes for biochemical and diagnostic applications.

Basic Information

Product Name	n-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenemethanamine
CAS No.	1454653-59-8
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	(3-((Methylamino)methyl)phenyl)boronic acid pinacol ester; 3-((Methylamino)methyl)benzeneboronic acid pinacol ester; 1-Methyl-1-(3-((methylamino)methyl)phenyl)boronate; N-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanamine; 3-(Aminomethyl)-N-methylbenzeneboronic acid pinacol ester; B-(3-((Methylamino)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzenemethanamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from oxidizing agents and strong acids. Due to its sensitivity, the container should be allowed to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.