Description

2,4-Dichloro-3-Ethynyl-1,5-Dimethoxybenzene is a specialized, multi-functional aromatic building block featuring both halogen and alkyne substituents. This compound matters for its versatility as a key intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures through cross-coupling and cycloaddition reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of novel drug candidates, particularly for constructing complex heterocyclic cores via Sonogashira or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, where the dichloro and ethynyl groups contribute to biological activity and molecular diversity.
• Material Science Precursor: Acts as a monomer or building block for the synthesis of advanced polymers, dendrimers, and organic electronic materials, leveraging its reactive ethynyl group for polymerization.
• Chemical Biology Probe Synthesis: Employed in creating tagged molecules or bioconjugates for studying biological pathways, where the alkyne handle allows for "click chemistry" attachment to azide-functionalized probes.
• Ligand and Catalyst Development: Utilized in the preparation of novel chelating ligands or organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,4-Dichloro-3-Ethynyl-1,5-Dimethoxybenzene
CAS No.	1453211-48-7
Molecular Formula	C10H8Cl2O2
Molecular Weight	231.08 g/mol
Synonyms	1,5-Dimethoxy-2,4-dichloro-3-ethynylbenzene; 3-Ethynyl-2,4-dichloro-1,5-dimethoxybenzene; 2,4-Dichloro-3-ethynyl-1,5-dimethoxy-benzene; Benzene, 2,4-dichloro-3-ethynyl-1,5-dimethoxy-; 1,5-Dimethoxy-2,4-dichlorobenzene-3-ethyne
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Each batch is characterized by modern analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, minimize exposure to light during handling and storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.