Description

2-Bromo-4-Chlorophenylboronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science: Employed in the creation of organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for exploring new synthetic routes and creating compound libraries.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Bromo-4-Chlorophenylboronic Acid
CAS No.	1451393-45-5
Molecular Formula	C6H5BBrClO2
Molecular Weight	235.27 g/mol
Synonyms	(2-Bromo-4-chlorophenyl)boronic acid; 2-Bromo-4-chlorobenzeneboronic acid; B-(2-Bromo-4-chlorophenyl)boronic acid; 2-Br-4-ClC6H3B(OH)2; Boronic acid, B-(2-bromo-4-chlorophenyl)-; 1451393-45-5
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chlorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.