Description

4-Bromo-2-Hydroxyphenylboronic Acid is a versatile organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a bromo and a hydroxyl substituent on the aromatic ring, enabling precise cross-coupling and derivatization reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality raw materials for complex synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific bromo- and hydroxyl-substituted biphenyl structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors for biochemical research and diagnostics.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Bromo-2-Hydroxyphenylboronic Acid
CAS No.	1451393-43-3
Molecular Formula	C6H6BBrO3
Molecular Weight	216.83 g/mol
Synonyms	(4-Bromo-2-hydroxyphenyl)boronic acid; 2-Hydroxy-4-bromophenylboronic acid; 4-Bromo-2-hydroxybenzeneboronic acid; B-(4-Bromo-2-hydroxyphenyl)boronic acid; 4-Bromosalicylboronic acid; 1451393-43-3; 4-Br-2-OH-PhB(OH)2
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Hydroxyphenylboronic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent lot-to-lot performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.