Description

5-Chloro-3-(Meththio)Phenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the chlorophenyl and thioether functionalities are pharmacologically relevant.
• Material Science Research: Building block for the development of organic electronic materials, such as ligands for catalysts or monomers for conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura reactions to form carbon-carbon bonds under mild conditions.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.

Basic Information

Product Name	5-Chloro-3-(Meththio)Phenylboronic Acid
CAS No.	1451392-52-1
Molecular Formula	C7H8BClO2S
Molecular Weight	202.46 g/mol
Synonyms	(5-Chloro-3-(methylthio)phenyl)boronic acid; 3-Methylthio-5-chlorophenylboronic acid; 5-Chloro-3-methylsulfanylbenzeneboronic acid; (3-Methylsulfanyl-5-chlorophenyl)boronic acid; Boronic acid, B-[5-chloro-3-(methylthio)phenyl]-; 1451392-52-1; 5-Chloro-m-(methylthio)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-(Meththio)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.