Description

4-(N,o-Dimethylhydroxylaminocarbonyl)-2-Chlorophenylboronic Acid is a specialized boronic acid derivative that serves as a high-value synthetic intermediate in advanced organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation, which is critical for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of biaryl and other carbon-carbon bonds in the presence of a palladium catalyst, a cornerstone reaction in modern organic synthesis.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aromatic structures.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs or sensors.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Item	Details
Product Name	4-(N,o-Dimethylhydroxylaminocarbonyl)-2-Chlorophenylboronic Acid
CAS No.	1451392-33-8
Molecular Formula	C9H11BClNO3
Molecular Weight	227.45 g/mol
Synonyms	2-Chloro-4-[(N,O-dimethylhydroxycarbamoyl)]phenylboronic Acid; [2-Chloro-4-[(dimethylamino)oxomethyl]phenyl]boronic Acid; 4-(N,O-Dimethylhydroxycarbamoyl)-2-chlorobenzeneboronic Acid; (2-Chloro-4-(N,O-dimethylhydroxycarbamoyl)phenyl)boronic Acid; B-[2-Chloro-4-[(dimethylamino)carbonyloxy]phenyl]boronic Acid; CAS 1451392-33-8
EINECS	Contact for details

Quality Control

Our 4-(N,o-Dimethylhydroxylaminocarbonyl)-2-Chlorophenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Handle and store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.