Description

2-Methyl-4-(Methoxymethoxy)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic ester building block essential for modern synthetic chemistry. This compound matters for its role in facilitating efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is critical for constructing complex molecular architectures. Pharmaceutical researchers, agrochemical developers, and advanced material scientists need it to create novel active ingredients and functional molecules with precision. Its protected boronate form offers enhanced stability, simplifying handling and storage compared to the free boronic acid.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific, complex aromatic structures for enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor in the synthesis of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-Methyl-4-(Methoxymethoxy)Phenylboronic Acid Pinacol Ester
CAS No.	1451392-30-5
Molecular Formula	C15H23BO4
Molecular Weight	278.15 g/mol
Synonyms	2-Methyl-4-(methoxymethoxy)phenylboronic acid pinacol ester; (2-Methyl-4-(methoxymethoxy)phenyl)boronic acid pinacol ester; 4-(Methoxymethoxy)-2-methylbenzeneboronic acid pinacol ester; 2-Methyl-4-MOM-phenylboronic acid pinacol ester; Pinacol [2-methyl-4-(methoxymethoxy)phenyl]boronate; B-[2-Methyl-4-(methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1451392-30-5
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-4-(Methoxymethoxy)Phenylboronic Acid Pinacol Ester is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request and are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation to prevent hydrolysis of the boronate ester. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.