Description

2,5-Difluoro-4-(Methoxymethoxy)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluoro and methoxymethoxy substituents confer specific biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for synthesizing organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and as a handle for bioconjugation in chemical biology.
• Chemical Library Production: A valuable reagent for medicinal chemistry and high-throughput screening libraries to explore new chemical space in drug discovery.

Basic Information

Product Name	2,5-Difluoro-4-(Methoxymethoxy)Phenylboronic Acid
CAS No.	1451392-29-2
Molecular Formula	C9H11BF2O4
Molecular Weight	231.99 g/mol
Synonyms	[4-(Methoxymethoxy)-2,5-difluorophenyl]boronic Acid; 2,5-Difluoro-4-(methoxymethoxy)benzeneboronic Acid; (2,5-Difluoro-4-(methoxymethoxy)phenyl)boronic Acid; B-[2,5-Difluoro-4-(methoxymethoxy)phenyl]boronic Acid; 1451392-29-2; 2,5-Difluoro-4-methoxymethoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-(Methoxymethoxy)Phenylboronic Acid is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.