Description

3-Methoxymethoxy-4-Methylphenylboronic Acid is a specialized organoboron building block of significant importance in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Ligand & Catalyst Development: Serves as a building block for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic semiconductors, where precise molecular structure is critical.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and target engagement.
• Custom Fine Chemical Manufacturing: A versatile intermediate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Product Name	3-Methoxymethoxy-4-Methylphenylboronic Acid
CAS No.	1451392-25-8
Molecular Formula	C9H13BO4
Molecular Weight	196.01 g/mol
Synonyms	(3-(Methoxymethoxy)-4-methylphenyl)boronic acid; 4-Methyl-3-(methoxymethoxy)benzeneboronic acid; 3-(Methoxymethoxy)-p-tolylboronic acid; Boronic acid, B-[3-(methoxymethoxy)-4-methylphenyl]-; 1451392-25-8; MOM-Protected Tolylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxymethoxy-4-Methylphenylboronic Acid is manufactured under strict quality management protocols. We ensure compliance with stringent in-house specifications, which are typical for high-value fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and elemental analysis, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting all test results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.