Description

4-Methoxy-2-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a pyrrolidine moiety that can impart desirable pharmacological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the pyrrolidine scaffold.
• Suzuki-Miyaura Cross-Coupling Reagent: Used in palladium-catalyzed reactions to form carbon-carbon bonds, enabling the construction of biaryl structures common in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity reagents for studying biological processes and protein function.

Basic Information

Product Name	4-Methoxy-2-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid
CAS No.	1451392-11-2
Molecular Formula	C₁₄H₂₂BNO₃
Molecular Weight	263.14 g/mol
Synonyms	[2-Methoxy-5-(pyrrolidin-1-ylmethyl)phenyl]boronic acid; 4-Methoxy-2-(1-pyrrolidinylmethyl)benzeneboronic acid; 2-Methoxy-5-((pyrrolidin-1-yl)methyl)phenylboronic acid; Boronic acid, B-[2-methoxy-5-(1-pyrrolidinylmethyl)phenyl]-; 5-(Pyrrolidin-1-ylmethyl)-2-methoxyphenylboronic acid; 1451392-11-2; 4-Methoxy-2-(pyrrolidin-1-ylmethyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.