Description

4-Bromo-3-Methylphenylboronic Acid n-Butyldiethanolamine Ester is a specialized organoboron reagent, specifically a boronic ester derivative, designed for enhanced stability and handling in advanced synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, particularly Suzuki-Miyaura couplings, where it offers improved solubility and reduced protodeboronation compared to its acid counterparts. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for constructing complex molecular architectures.

Application

• Key intermediate in Suzuki-Miyaura cross-coupling reactions for C-C bond formation in drug discovery.
• Building block for the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Precursor in the development of agrochemicals and specialty fine chemicals.
• Monomer or intermediate in the research and production of advanced materials, including organic electronic materials.
• Used in medicinal chemistry for creating compound libraries and structure-activity relationship (SAR) studies.
• Reagent in academic and industrial R&D for methodological development in organometallic catalysis.

Basic Information

Product Name	4-Bromo-3-Methylphenylboronic Acid n-Butyldiethanolamine Ester
CAS No.	1451391-62-0
Molecular Formula	C15H23BBrNO2
Molecular Weight	340.07 g/mol
Synonyms	4-Bromo-3-methylbenzeneboronic acid N-butyl diethanolamine ester; 2-[(4-Bromo-3-methylphenyl)boronic acid] N-butyl diethanolamine ester; B-(4-Bromo-3-methylphenyl)-N-butyl diethanolamine boronate; 4-Bromo-3-methylphenylboronic acid butyldiethanolamine ester; Boronic acid, B-(4-bromo-3-methylphenyl)-, N-butyl diethanolamine ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methylphenylboronic Acid n-Butyldiethanolamine Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.