Description

2,5-Dibromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate. Its core value proposition lies in enabling precise cross-coupling reactions, which are fundamental for constructing complex molecular architectures in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in the synthesis of novel active ingredients, functional polymers, and electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-couplings for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging its halogen and boronate functionality for structural diversification.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED emitters and charge-transport layers, due to its pyridine-boronate core.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global fine chemical market.

Basic Information

Item	Detail
Product Name	2,5-Dibromo-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1451391-18-6
Molecular Formula	C11H14BBr2NO2
Molecular Weight	373.86 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dibromopyridine; 2,5-Dibromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,5-Dibromopyridine-4-boronic acid pinacol ester; 4-Borono-2,5-dibromopyridine, pinacol ester; (2,5-Dibromopyridin-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dibromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.