Description

3-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a versatile and high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value proposition lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific chlorophenol-boronate motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organoboron catalysts used in asymmetric synthesis.
• Polymer and Material Science: Intermediate in the production of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new carbon-boron and carbon-carbon bond-forming methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	3-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	1451391-17-5
Molecular Formula	C12H16BClO3
Molecular Weight	254.52 g/mol
Synonyms	2-(3-Chloro-2-hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 3-Chloro-2-hydroxyphenylboronic acid pinacol ester; (3-Chloro-2-hydroxyphenyl)boronic acid pinacol ester; 2-(3-Chloro-2-hydroxy-phenyl)-[1,3,2]dioxaborolane,4,4,5,5-tetramethyl-; 1451391-17-5; 3-Chloro-2-(pinacolatoboryl)phenol
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and GC-MS, for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and specific tests are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.