Description

2-(2,6-Difluoro-3-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Research: Used to create complex, fluorinated aromatic structures found in next-generation herbicides, fungicides, and pesticides.
• Material Science: Serves as a monomer or building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Enables the efficient introduction of the 2,6-difluoro-3-nitrophenyl moiety into target molecules under mild conditions.
• Life Science Reagents: Employed in the development of biochemical probes, imaging agents, and diagnostic tools leveraging its boronate functionality.

Basic Information

Product Name	2-(2,6-Difluoro-3-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1451391-10-8
Molecular Formula	C₁₂H₁₄BF₂NO₄
Molecular Weight	285.05 g/mol
Synonyms	2,6-Difluoro-3-nitrophenylboronic acid pinacol ester; (2,6-Difluoro-3-nitrophenyl)boronic acid pinacol ester; 2-(2,6-Difluoro-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,6-Difluoro-3-nitrobenzeneboronic acid pinacol ester; 3-Nitro-2,6-difluorophenylboronic acid pinacol ester; Pinacol (2,6-difluoro-3-nitrophenyl)boronate; 1451391-10-8
EINECS	Contact for details

Quality Control

Every batch of 2-(2,6-Difluoro-3-Nitrophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems to ensure consistency and purity for research and production use. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.