Description

2,6-Dichloro-3-Nitrophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical protected boronic acid intermediate, enabling precise Suzuki-Miyaura cross-coupling reactions in complex molecule assembly. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in constructing complex biaryl and heterobiaryl structures via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides that require specific chloronitrophenyl motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or sensors, where the boronic ester group allows for modular construction.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, leveraging its coupling compatibility.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses producing bespoke organic compounds for client-specific projects.

Basic Information

Product Name	2,6-Dichloro-3-Nitrophenylboronic Acid Pinacol Ester
CAS No.	1451391-07-3
Molecular Formula	C12H14BCl2NO4
Molecular Weight	318.96 g/mol
Synonyms	2,6-Dichloro-3-nitrophenylboronic acid pinacol ester; (2,6-Dichloro-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2,6-Dichloro-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2,6-Dichloro-3-nitrophenyl)boronate; Boronic acid, B-(2,6-dichloro-3-nitrophenyl)-, 1,1-dimethylethyl ester; 2,6-Dichloro-3-nitrobenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-3-Nitrophenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.