Description

2-Amino-5-Isopropylphenylboronic Acid Pinacol Ester is a sophisticated boronic ester derivative, a protected form of a key arylboronic acid building block essential for modern synthetic chemistry. Its primary value lies in enabling precise carbon-carbon and carbon-heteroatom bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced material development. This high-purity intermediate is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including charge-transport layers and emissive materials in OLED displays.
• Ligand & Catalyst Design: Employed in the synthesis of novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Polymer Chemistry: Facilitates the incorporation of functional aromatic units into specialty polymers and dendrimers.
• Chemical Biology & Probe Development: Useful for creating bioconjugates and molecular probes for diagnostic and research applications.

Basic Information

Product Name	2-Amino-5-Isopropylphenylboronic Acid Pinacol Ester
CAS No.	1451390-90-1
Molecular Formula	C15H24BNO2
Molecular Weight	261.17 g/mol
Synonyms	2-Amino-5-isopropylbenzeneboronic acid pinacol ester; (2-Amino-5-isopropylphenyl)boronic acid pinacol ester; 2-Amino-5-(propan-2-yl)phenylboronic acid pinacol ester; 5-Isopropyl-2-aminophenylboronic acid pinacol ester; Boronic acid, B-[2-amino-5-(1-methylethyl)phenyl]-, 1,1-dimethylethyl ester; 2-Amino-5-isopropylphenyl-Bpin; 2-NH2-5-iPr-Ph-Bpin
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Isopropylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity, purity, and the absence of critical metallic impurities like palladium. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.