Description

(R)-1-Chloro-3-{[(4-Chlorophenyl)Methylene]Amino}Propan-2-Ol CAS NO 1450915-93-1 is a chiral, halogenated amino alcohol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and high-value building block for the construction of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and other performance materials requiring specific stereochemical configurations.
• Academic and R&D Laboratories: Utilized in methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	(R)-1-Chloro-3-{[(4-Chlorophenyl)Methylene]Amino}Propan-2-Ol
CAS No.	1450915-93-1
Molecular Formula	C10H11Cl2NO
Molecular Weight	232.11 g/mol
Synonyms	(R)-1-Chloro-3-((4-chlorobenzylidene)amino)propan-2-ol; (R)-1-Chloro-3-[(4-chlorobenzylidene)amino]-2-propanol; (R)-2-Chloro-1-[(4-chlorophenyl)methyleneamino]-3-propanol; 1450915-93-1; (R)-enantiomer of 1-Chloro-3-{[(4-Chlorophenyl)Methylene]Amino}Propan-2-Ol; (R)-Chlorinated Amino Propanol Derivative
EINECS	Contact for details

Quality Control

Our production of (R)-1-Chloro-3-{[(4-Chlorophenyl)Methylene]Amino}Propan-2-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analysis including HPLC for chiral purity, NMR for structural confirmation, and Karl Fischer titration for water content. Certificates of Analysis (COA) detailing all specifications are provided and we support custom synthesis to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.