Description

1-Bromovinylboronic Acid Mida Ester is a specialized, high-value organoboron reagent designed for advanced synthetic chemistry. This compound matters as a protected boronic acid derivative, offering superior stability and handling characteristics compared to its free acid counterpart, which is critical for complex multi-step synthesis. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling and the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex drug candidates, particularly in cross-coupling reactions to form carbon-carbon bonds.
• Agrochemical Research & Development: Used in the synthesis of novel active ingredients for crop protection products.
• Material Science: Employed in the development of organic electronic materials and advanced polymers.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, protected vinyl bromide coupling partner with aryl or vinyl halides.
• Medicinal Chemistry & Library Synthesis: Enables the efficient and reliable introduction of a functionalized vinyl group into target molecules.
• Process Chemistry & Scale-up: The MIDA ester protection enhances stability, making it suitable for multi-step synthetic sequences and larger-scale production.

Basic Information

Product Name	1-Bromovinylboronic Acid Mida Ester
CAS No.	1449377-16-5
Molecular Formula	C₉H₁₃BBrNO₄
Molecular Weight	289.92 g/mol
Synonyms	1-Bromoethenylboronic acid MIDA ester; (1-Bromovinyl)boronic acid MIDA ester; N-Methyliminodiacetic acid (1-bromovinyl)boronate; B-(1-Bromoethenyl)-N-methyliminodiacetic acid boronate; MIDA Boronate of 1-Bromovinylboronic Acid; 1-Bromovinyl MIDA Boronate; Vinyl Bromide MIDA Boronate; CAS 1449377-16-5
EINECS	Contact for details

Quality Control

Our 1-Bromovinylboronic Acid Mida Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is analyzed using advanced techniques including NMR and HPLC to confirm identity and assay. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated upon opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.