Description

4-(4-Methylpiperidin-1-Ylsulfonyl)Phenylboronic Acid is a specialized organoboron building block featuring a sulfonyl-linked piperidine moiety. This compound is valued for its dual functionality, serving as a key intermediate in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid partner for constructing biaryl and heterobiaryl structures central to medicinal chemistry.
• Chemical Biology & Proteomics: Used in the development of chemical probes and affinity ligands for target identification and validation.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its structural motif.
• Agrochemical Development: Serves as an intermediate in creating novel crop protection agents with enhanced efficacy.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	4-(4-Methylpiperidin-1-Ylsulfonyl)Phenylboronic Acid
CAS No.	1449132-62-0
Molecular Formula	C12H18BNO4S
Molecular Weight	283.15 g/mol
Synonyms	[4-(4-Methyl-1-piperidinylsulfonyl)phenyl]boronic acid; 4-(4-Methylpiperidine-1-sulfonyl)benzeneboronic acid; 4-(4-Methyl-1-piperidylsulfonyl)phenylboronic acid; 4-(N-4-Methylpiperidinylsulfonyl)phenylboronic acid; 1-(4-Boronophenylsulfonyl)-4-methylpiperidine; B-[4-[(4-Methyl-1-piperidinyl)sulfonyl]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Methylpiperidin-1-Ylsulfonyl)Phenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.