Description

4-Bromo-2,5-Difluoro-N,n-Dimethylbenzamide is a high-purity, multi-functional aromatic amide building block designed for advanced synthetic chemistry. This compound matters as a critical intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and fluorinated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the fluorine and bromine substituents for bioactivity.
• Material Science Research: Serves as a precursor for the creation of advanced organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Bromo-2,5-Difluoro-N,n-Dimethylbenzamide
CAS No.	1449008-10-9
Molecular Formula	C9H8BrF2NO
Molecular Weight	264.07 g/mol
Synonyms	4-Bromo-2,5-difluoro-N,N-dimethylbenzamide; N,N-Dimethyl-4-bromo-2,5-difluorobenzamide; 2,5-Difluoro-4-bromo-N,N-dimethylbenzamide; Benzamide, 4-bromo-2,5-difluoro-N,N-dimethyl-; 1449008-10-9; 4-Bromo-2,5-difluoro-N,N-dimethyl-benzamide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,5-Difluoro-N,n-Dimethylbenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.