Description

2-(Benzyloxy)-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is valued for its role in facilitating key carbon-carbon bond-forming reactions, enabling the efficient synthesis of complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical boron-containing reagent for constructing biaryl and heterobiaryl structures in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Serves as a key precursor for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, due to its functionalized aromatic core.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Item	Details
Product Name	2-(Benzyloxy)-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1448894-65-2
Molecular Formula	C20H22BNO3
Molecular Weight	335.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(benzyloxy)benzonitrile; 2-(Benzyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2-Benzyloxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; Benzonitrile, 2-(benzyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; PINACOL 2-(BENZYLOXY)-4-CYANOPHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.